CHRISTINA BOWERS PH.D
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  • Group 4 Project

topic 7.1 DNA structure and replication

Essential idea:
  • The structure of DNA is ideally suited to its function

7.1U1:  Nucleosomes help to supercoil the DNA.
7.1U2:  DNA structure suggested a mechanism for DNA replication.
7.1U3:  DNA polymerases can only add nucleotides to the 3' end of a primer.
7.1U4:  DNA replication is continuous on the leading strand, and discontinuous on the lagging strand.
7.1U5:  DNA replication is carried out by a complex system of enzymes.
7.1U6:  Some regions of DNA do not code for proteins but have other important functions.


7.1A1:  Rosalind Franklin and Maurice Wilkin's investigation of DNA by X-ray diffraction.
7.1A2:  Use of nucleotides containing dideoxyribonucleic acid to stop DNA replication in preparation of samples for base sequencing.
7.1A3:  Tandem repeats are used in DNA profiling.

7.1Skill 1:  Analysis of results of the Hershey and Chase experiment to provide evidence that DNA is the genetic material.
7.1Skill 2:  Utilization of molecular visualization software to analyse the association between protein and DNA within a nucleosome.
LIfe is wonderfully complicated.   Stay curious.  Be skeptical.    And above all, ask many questions!